c.curionodeThe Nobel Archive

2026 · Chemistry

When molecules choose a handedness

Chemical reactions can amplify a tiny preference between two mirror-image forms.

ChiralityCatalysisMirror molecules
2026Chemistry

Visual guide

The prize, pictured

Infographic explaining When molecules choose a handedness
Original AI-generated infographic. A conceptual overview; the explanations and sources below provide context.
Read the poster text

Chemical reactions can magnify molecular handedness.

  1. Mirror-image forms

    Some molecules have left and right versions.

  2. A small preference

    Catalysis can favour one form.

  3. Amplify the imbalance

    Autocatalysis helps produce more of the same form.

A possible route to asymmetry, not proof of life’s exact origin.

01 · The discovery

The idea, in everyday language

Some molecules come in forms like left and right hands: the same parts, arranged as mirror images. Their interactions with living systems can differ.

Kagan studied how a catalyst’s small preference can produce a larger imbalance. Soai developed reactions whose products help produce more of the same form, amplifying that preference.

Why it matters

Controlling molecular handedness matters in synthesis, including the preparation of pharmaceuticals.

02 · The people

Who brought the idea to life?

Illustrated portrait of Kenso Soai

Kenso Soai

Prize share · 1/2

He developed asymmetric autocatalysis that amplifies a small initial imbalance into a large excess of one mirror-image product.

Read the biography ↗

03 · Years in the making

The path here

  1. 1986

    Kagan reports nonlinear effects.

  2. 1995

    Soai reports asymmetric autocatalysis.

  3. 2026

    The discoveries receive the Chemistry prize.

04 · Read further

From the original sources

Original explanations by Curionode, based on the official records below. Biographical details and affiliations refer to the award year.

  1. Official award announcement kva.se
  2. Royal Society of Chemistry overview rsc.org

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